Mercedes-Benz S 580e 4MATIC vs 750Li — full comparison

Mercedes-Benz S 580e 4MATIC

Sedan · Phev · AWD

vs

750Li

Sedan · Gasoline · FWD

Mercedes-Benz S 580e 4MATIC

Car A

Mercedes-Benz S 580e 4MATIC

The Mercedes-Benz S 580e 4MATIC blends high performance with standout plug-in efficiency and a useful 100 km electric range. It suits luxury-focused drivers who want quiet daily EV use with all-weather confidence for long trips.

5 seatsSedanPhev5-star safety2.5 L/100km510 hpAWDPlug-in hybrid

750Li

Car B

750Li

A spacious luxury saloon with serious power and a huge trunk, it excels on long road trips and premium family duty. High pricing and a gasoline FWD setup make it less compelling for city-heavy or efficiency-first driving.

5 seatsSedanGasoline5-star safety

Why compared cross branddifferent powertrainsame body typesame seatssimilar price

Usage fit

Family 55 / 67

City 34 / 22

Budget / value 25 / 29

Road trip 71 / 67

Performance 47 / 39

Cargo 30 / 33

Practical 39 / 44

Premium 79 / 73

Winter 70 / 30

Scores out of 100. Blue = Mercedes-Benz S 580e 4MATIC · Orange = 750Li

Specs side-by-side

Spec Mercedes-Benz S 580e 4MATIC 750Li

Values are representative — confirm for your market and trim.

Pros & cons

Mercedes-Benz S 580e 4MATIC

Up to 100 km electric-only range covers most commutes and enables quiet city driving
Efficient for its class, with a rated 2.5 combined consumption when charged regularly
Strong performance (510 hp, 750 Nm, 0–100 km/h in 4.1 s) for confident passing
AWD stability plus a 550 L trunk and five seats suit road trips and growing families
High purchase price limits appeal to budget-focused buyers
Efficiency benefits shrink if you can’t charge frequently
100 km EV range is shorter than a full EV for all-electric long trips
Not ideal for cargo-heavy use, despite a usable 550 L trunk

750Li

Strong acceleration and power for confident overtakes and relaxed cruising
Spacious 5-seat cabin and 600 L trunk suit family travel and luggage
Comfort-focused luxury makes long-distance trips easy
Safety ranks as a key strength for this model line
Premium price sits at the expensive end of the segment
Front-wheel-drive layout may not suit performance purists
Gasoline-only powertrain lacks hybrid or EV efficiency benefits
Optimized for highways more than tight city driving and parking

Verdict

Pick Mercedes-Benz S 580e 4MATIC if…

Best fuel economy

Mercedes-Benz S 580e 4MATIC uses 2.5 L/100km vs 10.0 — a meaningful saving if you cover high mileage.

Pick 750Li if…

Performance & capability

750Li is the choice if you want more power, speed, or all-weather capability.

Related comparisons