Mercedes-Benz S 450 4MATIC
Sedan · Gasoline · AWD
vs
Audi S4 Sedan
Sedan · Gasoline · AWD
Mercedes-Benz S 450 4MATIC
Car A
Mercedes-Benz S 450 4MATIC
The Mercedes-Benz S 450 4MATIC pairs strong AWD performance with room for five, making it well-suited to road trips and winter use. It offers good value in its segment given its 362 hp, 5.4 s 0–100 km/h, and a usable 525 L trunk.
5 seatsSedanGasoline5-star safety362 hpAWD
Audi S4 Sedan
Car B
Audi S4 Sedan
The Audi S4 Sedan pairs strong V6 power and AWD traction with five-seat practicality, making it a confident choice for growing families and road trips. It delivers quick acceleration and efficient-for-its-class consumption, though cargo space and track-day performance aren’t its focus.
5 seatsSedanGasoline5-star safety7.4 L/100kmAWD
Why compared cross brandsame body typesame powertrainsame seatssimilar price

Usage fit

Family 55 / 63
City 31 / 47
Budget / value 32 / 55
Road trip 69 / 57
Performance 43 / 40
Cargo 29 / 26
Practical 30 / 44
Premium 61 / 53
Winter 70 / 66

Scores out of 100. Blue = Mercedes-Benz S 450 4MATIC · Orange = Audi S4 Sedan

Specs side-by-side

Spec Mercedes-Benz S 450 4MATIC Audi S4 Sedan
Values are representative — confirm for your market and trim.

Pros & cons

Mercedes-Benz S 450 4MATIC

  • AWD traction boosts confidence for winter driving and long-distance trips.
  • Strong performance (362 hp, 500 Nm, 0–100 km/h in 5.4 s) for easy passing and highway cruising.
  • Seats five with a 525 L trunk, fitting family travel and weekend luggage.
  • High safety ranking in the signals adds peace of mind.

Audi S4 Sedan

  • Strong V6 output (354 hp, 500 Nm) with 4.6 s 0–100 km/h for confident passing
  • AWD traction adds assurance in winter and mixed conditions
  • Five seats and a 480 L trunk fit growing-family and road-trip needs
  • Efficient for its class at 7.4 combined and good value in its segment

Verdict

Pick Mercedes-Benz S 450 4MATIC if…
Efficiency & everyday ease
Mercedes-Benz S 450 4MATIC is the choice if fuel economy and city-friendly driving are your priority.
Pick Audi S4 Sedan if…
Performance & capability
Audi S4 Sedan is the choice if you want more power, speed, or all-weather capability.

Related comparisons