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Mercedes-Benz E 350
Sedan · Gasoline · FWD
vs
Mercedes-Benz CLS 400
Sedan · Gasoline · FWD
Mercedes-Benz E 350
Car A
Mercedes-Benz E 350
The Mercedes-Benz E 350 blends strong performance with family-ready space, making it well-suited to growing families and long trips. Efficiency is solid for its class at 8 L/100 km, though the FWD layout may lessen winter appeal.
5 seatsSedanGasoline5-star safety8 L/100km
Mercedes-Benz CLS 400
Car B
Mercedes-Benz CLS 400
The Mercedes-Benz CLS 400 blends strong V6 performance with space and comfort for long trips, backed by a 520‑liter trunk and five seats. Its premium pricing and FWD layout make it less compelling for cargo-heavy use or harsh-winter regions that favor AWD.
5 seatsSedanGasoline5-star safety333 hp
Why compared same body typesame brandsame powertrainsame seatssimilar price

Usage fit

Family 64 / 54
City 33 / 31
Budget / value 49 / 32
Road trip 63 / 63
Performance 36 / 35
Cargo 30 / 29
Practical 44 / 31
Premium 61 / 62
Winter 30 / 30

Scores out of 100. Blue = Mercedes-Benz E 350 · Orange = Mercedes-Benz CLS 400

Specs side-by-side

Spec Mercedes-Benz E 350 Mercedes-Benz CLS 400
Values are representative — confirm for your market and trim.

Pros & cons

Mercedes-Benz E 350

  • Quick acceleration and strong passing power from 320 hp and a 5.9 s 0–100 km/h
  • Five seats and a 540 L trunk suit family duties and road-trip luggage
  • Efficient for its class at 8 L/100 km for a gasoline powertrain
  • Good value in its segment at this price point given its performance and space

Mercedes-Benz CLS 400

  • Strong V6 performance makes highway passing easy
  • 520‑liter trunk and five seats support road trips and growing families
  • Efficient for its class at 8.4 L/100 km combined
  • Ranks well for safety in its class

Verdict

Pick Mercedes-Benz E 350 if…
Best fuel economy
Mercedes-Benz E 350 uses 8.0 L/100km vs 8.4 — a meaningful saving if you cover high mileage.
Pick Mercedes-Benz CLS 400 if…
More power
Mercedes-Benz CLS 400 puts out 333 hp vs 320 — meaningfully quicker and more confident on motorways.

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