Mercedes-Benz E 350 vs Mercedes-Benz AMG E 43 — full comparison

Mercedes-Benz E 350

Sedan · Gasoline · FWD

vs

Mercedes-Benz AMG E 43

Sedan · Gasoline · FWD

Mercedes-Benz E 350

Car A

Mercedes-Benz E 350

The Mercedes-Benz E 350 blends strong performance with family-ready space, making it well-suited to growing families and long trips. Efficiency is solid for its class at 8 L/100 km, though the FWD layout may lessen winter appeal.

5 seatsSedanGasoline5-star safety8 L/100km

Mercedes-Benz AMG E 43

Car B

Mercedes-Benz AMG E 43

The Mercedes-Benz AMG E 43 blends serious V6 biturbo pace with five-seat practicality and a generous 540 L trunk for premium-minded travelers. It’s quick yet reasonably efficient for its class at 9 L/100 km.

5 seatsSedanGasoline5-star safety396 hp

Why compared same body typesame brandsame powertrainsame seatssimilar price

Usage fit

Family 64 / 63

City 33 / 29

Budget / value 49 / 40

Road trip 63 / 63

Performance 36 / 36

Cargo 30 / 30

Practical 44 / 41

Premium 61 / 65

Winter 30 / 30

Scores out of 100. Blue = Mercedes-Benz E 350 · Orange = Mercedes-Benz AMG E 43

Specs side-by-side

Spec Mercedes-Benz E 350 Mercedes-Benz AMG E 43

Values are representative — confirm for your market and trim.

Pros & cons

Mercedes-Benz E 350

Quick acceleration and strong passing power from 320 hp and a 5.9 s 0–100 km/h
Five seats and a 540 L trunk suit family duties and road-trip luggage
Efficient for its class at 8 L/100 km for a gasoline powertrain
Good value in its segment at this price point given its performance and space
Front-wheel drive may not satisfy buyers seeking extra winter traction
If you often carry oversized or bulky items, the trunk may be limiting
At 8 L/100 km, there are more efficient options if fuel economy is your top priority
The price may feel high if you don’t need this level of performance

Mercedes-Benz AMG E 43

Explosive acceleration (0–100 km/h in 4.6 s) backed by a 396‑hp V6 biturbo.
Five seats and a 540 L trunk suit road trips and growing families.
Signals indicate strong standing for horsepower and safety in its segment.
9 L/100 km combined is efficient for its class given the performance.
Front‑wheel drive may disappoint buyers wanting all‑wheel‑drive traction.
At 72,600, it sits well above mainstream price points.
Usage signals suggest it’s less at home in stop‑start city driving.
Despite a big trunk, it isn’t ideal for cargo‑heavy or bulky loads.

Verdict

Pick Mercedes-Benz E 350 if…

Best fuel economy

Mercedes-Benz E 350 uses 8.0 L/100km vs 9.0 — a meaningful saving if you cover high mileage.

Pick Mercedes-Benz AMG E 43 if…

More power

Mercedes-Benz AMG E 43 puts out 396 hp vs 320 — meaningfully quicker and more confident on motorways.

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