Mercedes-Benz CLS 450 vs Mercedes-Benz E 350

Mercedes-Benz CLS 450

Sedan · Gasoline · FWD

Mercedes-Benz E 350

Sedan · Gasoline · FWD

Car A

Mercedes-Benz CLS 450

The Mercedes-Benz CLS 450 blends strong turbo inline-6 pace (0–100 km/h in 4.5 s) with five-seat practicality and a 520-liter trunk for growing families and road trips. Premium pricing and front-wheel drive make it best for buyers who value performance and safety rankings over cargo-heavy or winter-focused needs.

5 seatsSedanGasoline5-star safety367 hp

Car B

Mercedes-Benz E 350

The Mercedes-Benz E 350 blends strong performance with family-ready space, making it well-suited to growing families and long trips. Efficiency is solid for its class at 8 L/100 km, though the FWD layout may lessen winter appeal.

5 seatsSedanGasoline5-star safety8 L/100km

Why compared same body typesame powertrainsame seatssame usage profilesimilar price

Usage fit

Family 64 / 64

City 31 / 33

Budget / value 46 / 49

Road trip 63 / 63

Performance 35 / 36

Cargo 29 / 30

Practical 44 / 44

Premium 64 / 61

Winter 30 / 30

Scores out of 100. Blue = Mercedes-Benz CLS 450 · Orange = Mercedes-Benz E 350

Specs side-by-side

Spec Mercedes-Benz CLS 450 Mercedes-Benz E 350

Values are representative — confirm for your market and trim.

Pros & cons